Iron Disorders Institute Guide to Hemochromatosis: A Genetic Disorder of Iron Metabolism
Author: Wylie Burk
Hemochromatosis is one of modern medicine's greatest oversights. A disorder that few Americans are able to pronounce at first glance, it is an inherited disorder of iron metabolism, not a blood disease, that can be fatal if not detected in time. Commonly misdiagnosed as arthritis, diabetes, heart disease, impotence, depression, and liver disease, hereditary hemochromatosis is common in people of northern European descent and is most prominent among the Scotch-Irish.
Undetected hemochromatosis frequently is fatal, and that is why it is emerging as one of the most important health issues of the new millenium. It's real, it's common, and it can kill you.
The Iron Disorders Institute Guide to Hemochromatosis is a reference book for home use. It contains helpful charts, diet and nutrition information, treatment guidelines, a glossary of terms, and compelling personal stories of people living with this disorder. Written by the top researchers and experts in university and research hospitals from all over the United States, it is destined to become the definitive source for information about the disorder for millions of families worldwide.
Author Biography: Wylie Burke, PH.D., M.D., is Associate Professor and Chair of the Department of Medical History in the Department of Medicine, Division of Medical Genetics, at the University of Washington, Seattle. She was the founding director of the Women's Health Care Center at UW Medical Center-Roosevelt. P.D. Phatak, M.D., is Head of Hematology and Medical Oncology at Rochester General Hospital. He has served as Medical Advisor to Mary Gooley Hemophilia Center and is the lead investigator of a population screening program for hemochromatosis at Rochester General Hospital. E.D. Weinberg, PH.D., is professor of Microbiology, Indiana University. A leading expert in infectious disease and cancer, he has researched the subject of iron's relationship to cancer for more than forty years.
Table of Contents:
Foreword | ix | |
Acknowledgments | xiii | |
Introduction - A Message from the Founders of the Iron Disorders Institute | xv | |
Part 1 | Iron--A Little Bit Goes a Long Way | |
1 | Hemochromatosis--Not Just a Rare, Older Man's Disease | 3 |
2 | Iron in Your Body | 11 |
3 | Our One-Sided View of Iron | 21 |
4 | Iron Imbalances--Not Always What They Seem | 23 |
Part 2 | Detecting and Diagnosing Hemochromatosis | |
5 | Why Some Doctors Miss the Diagnosis of Hemochromatosis | 37 |
6 | How Do I Know If I Have Iron Overload? | 43 |
7 | Clues That Can Lead to Diagnosis | 51 |
8 | Benefits of Screening for Hemochromatosis | 59 |
9 | HFE Mutations Explained | 65 |
10 | The Role of a Genetics Counselor | 69 |
11 | Who Is a Candidate for Genetic Testing? | 71 |
Part 3 | Symptoms of Iron Overload | |
12 | Studies, Surveys, and Patient Interviews | 77 |
13 | Living with Undetected Hemochromatosis | 83 |
14 | Body Systems and Excess Iron | 105 |
Part 4 | Hemochromatosis, Not the Only Iron Loading Disorder | |
15 | Other Conditions That Can Cause Iron Overload Disease | 129 |
16 | Various Roles of Ferritin | 139 |
Part 5 | Battles with Hemochromatosis--Won or Lost | |
17 | Vital Messages from Two Carriers--The Stories of Chris Main and Charlie Herr | 147 |
18 | Mother, Wife, and Friend--The Story of Irene de Sterke | 153 |
19 | Poet, Brother, Husband, and Son--The Story of Sam Martin | 159 |
20 | One of the First Documented U.S. Cases--The Story of Jack Ritter | 163 |
21 | Two Brothers Spared, Thanks to One Sharp Physician--The Story of Cliff and Chris | 171 |
22 | One Man's Advice--The Story of Tug Nix | 175 |
23 | One More Reason to Stop Smoking--The Story of Two Swiss Children | 179 |
Part 6 | Taking Care of Yourself | |
24 | Individualizing Treatment | 183 |
25 | Therapeutic Phlebotomy Explained | 193 |
26 | Treatment Options | 197 |
27 | Why Is the Blood Thrown Away? | 209 |
28 | Keeping Iron in Balance with Diet and Preventive Measures | 213 |
Part 7 | Support Across the USA and Around the World | |
29 | About the Iron Disorders Institute | 243 |
30 | International Alliances | 255 |
31 | Role of Government Health Agencies | 267 |
Commonly Asked Questions and Answers | 281 | |
Glossary of Terms | 289 | |
Contacts | 331 | |
Bibliography | 347 | |
Index | 355 |
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